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NPPES vs Open Disease

Same instrument, two spec sheets — measured, not claimed.

APINPPESNEW—Open DiseaseNEW—
Uptime · 30d
Uptime · 90d—%—%
Uptime · 30d—%—%
P50 · ms——
P95 · ms——
Authnonenone
CORSnoyes
HTTPSyesyes
Card requirednono
Commercial useyesunclear
Data licenseU.S. Government (public NPI data)Unverified (sources vary; see project repo)
Free tierFree — no key requiredFree — no key required
Rate limitUnpublishedUnpublished
In directory since2026-07-052026-07-05
operationalpartialdownno data

NPPES vs Open Disease: common questions

Which is more reliable, NPPES or Open Disease?

On our scheduled checks, Open Disease leads on measured uptime — NPPES at —% versus Open Disease at —% over 90 days. These are our own probe results, not provider claims; the uptime bars above show the day-by-day record for both.

Do NPPES and Open Disease need an API key?

Neither needs a paid key — NPPES is callable with no signup, and Open Disease is callable with no signup. Both are quick to prototype with; rate limits still apply.

Can I call NPPES and Open Disease from the browser?

Only Open Disease is browser-friendly — it returns CORS headers over HTTPS. NPPES needs a server-side call or proxy, so factor that into which one fits a front-end project.

Are NPPES and Open Disease free for commercial use?

NPPES allows commercial use on its free tier, and Open Disease has unclear commercial terms. We track service terms and the data license as separate fields — see the Commercial use and Data license rows above, and confirm both before shipping either in a paid product.