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MedlinePlus Genetics vs Spoonacular

Same instrument, two spec sheets — measured, not claimed.

APIMedlinePlus GeneticsNEW—SpoonacularNEW—
Uptime · 30d
Uptime · 90d—%—%
Uptime · 30d—%—%
P50 · ms——
P95 · ms——
AuthnoneapiKey
CORSyesyes
HTTPSyesyes
Card requirednono
Commercial useunclearunclear
Data licenseU.S. National Library of Medicine (see NLM terms)Unverified
Free tierFree — no key requiredFree — 50 points/day
Rate limitUnpublished50 points/day on free plan
In directory since2026-07-052026-07-05
operationalpartialdownno data

MedlinePlus Genetics vs Spoonacular: common questions

Which is more reliable, MedlinePlus Genetics or Spoonacular?

On our scheduled checks, Spoonacular leads on measured uptime — MedlinePlus Genetics at —% versus Spoonacular at —% over 90 days. These are our own probe results, not provider claims; the uptime bars above show the day-by-day record for both.

Do MedlinePlus Genetics and Spoonacular need an API key?

MedlinePlus Genetics needs no key, while Spoonacular requires a free API key. If you want to start calling without signup, reach for MedlinePlus Genetics first.

Can I call MedlinePlus Genetics and Spoonacular from the browser?

Yes — both MedlinePlus Genetics and Spoonacular send CORS headers over HTTPS, so front-end code can fetch either directly with no backend proxy. That makes them easy to swap in a client-side app while you compare responses.

Are MedlinePlus Genetics and Spoonacular free for commercial use?

MedlinePlus Genetics has unclear commercial terms, and Spoonacular has unclear commercial terms. We track service terms and the data license as separate fields — see the Commercial use and Data license rows above, and confirm both before shipping either in a paid product.