MedlinePlus Genetics vs OpenF1

Same instrument, two spec sheets — measured, not claimed.

Uptime · 30d
Uptime · 90d99.02%47.1%
Uptime · 30d98.3%41.7%
P50 · ms1877747
P95 · ms49423525
Authnonenone
CORSyesyes
HTTPSyesyes
Card requirednono
Commercial useunclearunclear
Data licenseU.S. National Library of Medicine (see NLM terms)Unverified
Free tierFree — no key requiredFree & open (historical); real-time may require a free account
Rate limitUnpublishedRetry-After: 60s
In directory since2026-07-052026-07-05
operationalpartialdownno data

MedlinePlus Genetics vs OpenF1: common questions

Which is more reliable, MedlinePlus Genetics or OpenF1?

On our scheduled checks, MedlinePlus Genetics leads on measured uptime — MedlinePlus Genetics at 99.02% versus OpenF1 at 47.1% over 90 days. These are our own probe results, not provider claims; the uptime bars above show the day-by-day record for both.

Which is faster, MedlinePlus Genetics or OpenF1?

OpenF1 has the lower median latency in our checks — MedlinePlus Genetics responds in 1877 ms versus OpenF1 at 747 ms (P50). Tail latency (P95) is in the table above; for most workloads the median is the number that shapes how the API feels.

Do MedlinePlus Genetics and OpenF1 need an API key?

Neither needs a paid key — MedlinePlus Genetics is callable with no signup, and OpenF1 is callable with no signup. Both are quick to prototype with; rate limits still apply.

Can I call MedlinePlus Genetics and OpenF1 from the browser?

Yes — both MedlinePlus Genetics and OpenF1 send CORS headers over HTTPS, so front-end code can fetch either directly with no backend proxy. That makes them easy to swap in a client-side app while you compare responses.

Are MedlinePlus Genetics and OpenF1 free for commercial use?

MedlinePlus Genetics has unclear commercial terms, and OpenF1 has unclear commercial terms. We track service terms and the data license as separate fields — see the Commercial use and Data license rows above, and confirm both before shipping either in a paid product.