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MedlinePlus Genetics vs Open Brewery DB

Same instrument, two spec sheets — measured, not claimed.

APIMedlinePlus GeneticsNEW—Open Brewery DBNEW—
Uptime · 30d
Uptime · 90d—%—%
Uptime · 30d—%—%
P50 · ms——
P95 · ms——
Authnonenone
CORSyesyes
HTTPSyesyes
Card requirednono
Commercial useunclearunclear
Data licenseU.S. National Library of Medicine (see NLM terms)Unverified (open dataset)
Free tierFree — no key requiredFree — no key
Rate limitUnpublished120 req/window · 114 remaining
In directory since2026-07-052026-07-05
operationalpartialdownno data

MedlinePlus Genetics vs Open Brewery DB: common questions

Which is more reliable, MedlinePlus Genetics or Open Brewery DB?

On our scheduled checks, Open Brewery DB leads on measured uptime — MedlinePlus Genetics at —% versus Open Brewery DB at —% over 90 days. These are our own probe results, not provider claims; the uptime bars above show the day-by-day record for both.

Do MedlinePlus Genetics and Open Brewery DB need an API key?

Neither needs a paid key — MedlinePlus Genetics is callable with no signup, and Open Brewery DB is callable with no signup. Both are quick to prototype with; rate limits still apply.

Can I call MedlinePlus Genetics and Open Brewery DB from the browser?

Yes — both MedlinePlus Genetics and Open Brewery DB send CORS headers over HTTPS, so front-end code can fetch either directly with no backend proxy. That makes them easy to swap in a client-side app while you compare responses.

Are MedlinePlus Genetics and Open Brewery DB free for commercial use?

MedlinePlus Genetics has unclear commercial terms, and Open Brewery DB has unclear commercial terms. We track service terms and the data license as separate fields — see the Commercial use and Data license rows above, and confirm both before shipping either in a paid product.