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MedlinePlus Genetics vs LAPIS

Same instrument, two spec sheets — measured, not claimed.

APIMedlinePlus GeneticsNEW—LAPISNEW—
Uptime · 30d
Uptime · 90d—%—%
Uptime · 30d—%—%
P50 · ms——
P95 · ms——
Authnonenone
CORSyesyes
HTTPSyesyes
Card requirednono
Commercial useunclearunclear
Data licenseU.S. National Library of Medicine (see NLM terms)Open sequence data (GenBank/Nextstrain-derived); Unverified
Free tierFree — no key requiredFree — no key (open instance)
Rate limitUnpublishedUnpublished
In directory since2026-07-052026-07-05
operationalpartialdownno data

MedlinePlus Genetics vs LAPIS: common questions

Which is more reliable, MedlinePlus Genetics or LAPIS?

On our scheduled checks, LAPIS leads on measured uptime — MedlinePlus Genetics at —% versus LAPIS at —% over 90 days. These are our own probe results, not provider claims; the uptime bars above show the day-by-day record for both.

Do MedlinePlus Genetics and LAPIS need an API key?

Neither needs a paid key — MedlinePlus Genetics is callable with no signup, and LAPIS is callable with no signup. Both are quick to prototype with; rate limits still apply.

Can I call MedlinePlus Genetics and LAPIS from the browser?

Yes — both MedlinePlus Genetics and LAPIS send CORS headers over HTTPS, so front-end code can fetch either directly with no backend proxy. That makes them easy to swap in a client-side app while you compare responses.

Are MedlinePlus Genetics and LAPIS free for commercial use?

MedlinePlus Genetics has unclear commercial terms, and LAPIS has unclear commercial terms. We track service terms and the data license as separate fields — see the Commercial use and Data license rows above, and confirm both before shipping either in a paid product.