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ES·pera API vs MedlinePlus Genetics

Same instrument, two spec sheets — measured, not claimed.

APIES·pera APIDYING37MedlinePlus GeneticsHEALTHY83
Uptime · 30d
Uptime · 90d0.0%99.44%
Uptime · 30d0.0%100%
P50 · ms—622
P95 · ms—4435
Authnonenone
CORSnoyes
HTTPSyesyes
Card requirednono
Commercial useunclearunclear
Data licenseU.S. National Library of Medicine (see NLM terms)
Free tierFree — no key required
Rate limitUnpublished
In directory since2026-09-212026-07-05
operationalpartialdownno data

ES·pera API vs MedlinePlus Genetics: common questions

Which is more reliable, ES·pera API or MedlinePlus Genetics?

On our scheduled checks, MedlinePlus Genetics leads on measured uptime — ES·pera API at 0.0% versus MedlinePlus Genetics at 99.44% over 90 days. These are our own probe results, not provider claims; the uptime bars above show the day-by-day record for both.

Do ES·pera API and MedlinePlus Genetics need an API key?

Neither needs a paid key — ES·pera API is callable with no signup, and MedlinePlus Genetics is callable with no signup. Both are quick to prototype with; rate limits still apply.

Can I call ES·pera API and MedlinePlus Genetics from the browser?

Only MedlinePlus Genetics is browser-friendly — it returns CORS headers over HTTPS. ES·pera API needs a server-side call or proxy, so factor that into which one fits a front-end project.

Are ES·pera API and MedlinePlus Genetics free for commercial use?

ES·pera API has unclear commercial terms, and MedlinePlus Genetics has unclear commercial terms. We track service terms and the data license as separate fields — see the Commercial use and Data license rows above, and confirm both before shipping either in a paid product.