ClinicalTrials.gov vs OpenF1
Same instrument, two spec sheets — measured, not claimed.
ClinicalTrials.gov vs OpenF1: common questions
Which is more reliable, ClinicalTrials.gov or OpenF1?
On our scheduled checks, ClinicalTrials.gov leads on measured uptime — ClinicalTrials.gov at 99.02% versus OpenF1 at 47.1% over 90 days. These are our own probe results, not provider claims; the uptime bars above show the day-by-day record for both.
Which is faster, ClinicalTrials.gov or OpenF1?
ClinicalTrials.gov has the lower median latency in our checks — ClinicalTrials.gov responds in 243 ms versus OpenF1 at 747 ms (P50). Tail latency (P95) is in the table above; for most workloads the median is the number that shapes how the API feels.
Do ClinicalTrials.gov and OpenF1 need an API key?
Neither needs a paid key — ClinicalTrials.gov is callable with no signup, and OpenF1 is callable with no signup. Both are quick to prototype with; rate limits still apply.
Can I call ClinicalTrials.gov and OpenF1 from the browser?
Yes — both ClinicalTrials.gov and OpenF1 send CORS headers over HTTPS, so front-end code can fetch either directly with no backend proxy. That makes them easy to swap in a client-side app while you compare responses.
Are ClinicalTrials.gov and OpenF1 free for commercial use?
ClinicalTrials.gov has unclear commercial terms, and OpenF1 has unclear commercial terms. We track service terms and the data license as separate fields — see the Commercial use and Data license rows above, and confirm both before shipping either in a paid product.