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ClinicalTrials.gov vs F1 API

Same instrument, two spec sheets — measured, not claimed.

APIClinicalTrials.govNEW—F1 APINEW—
Uptime · 30d
Uptime · 90d—%—%
Uptime · 30d—%—%
P50 · ms——
P95 · ms——
Authnonenone
CORSyesyes
HTTPSyesyes
Card requirednono
Commercial useunclearunclear
Data licenseUnverifiedUnverified
Free tierFree — limits not publishedFree — limits not published
Rate limitUnpublishedUnpublished
In directory since2026-07-052026-07-05
operationalpartialdownno data

ClinicalTrials.gov vs F1 API: common questions

Which is more reliable, ClinicalTrials.gov or F1 API?

On our scheduled checks, F1 API leads on measured uptime — ClinicalTrials.gov at —% versus F1 API at —% over 90 days. These are our own probe results, not provider claims; the uptime bars above show the day-by-day record for both.

Do ClinicalTrials.gov and F1 API need an API key?

Neither needs a paid key — ClinicalTrials.gov is callable with no signup, and F1 API is callable with no signup. Both are quick to prototype with; rate limits still apply.

Can I call ClinicalTrials.gov and F1 API from the browser?

Yes — both ClinicalTrials.gov and F1 API send CORS headers over HTTPS, so front-end code can fetch either directly with no backend proxy. That makes them easy to swap in a client-side app while you compare responses.

Are ClinicalTrials.gov and F1 API free for commercial use?

ClinicalTrials.gov has unclear commercial terms, and F1 API has unclear commercial terms. We track service terms and the data license as separate fields — see the Commercial use and Data license rows above, and confirm both before shipping either in a paid product.